FIVM Series presents: Glässer's disease prevention - past, present and future

Haemophilus parasuis is a bacterium that triggers Glässer’s disease, an important bacterial disease of swine.  Glässer’s disease is a systemic inflammatory condition that affects mainly young pigs in the nursery phase.

On Friday, September 14, Dr. Rafael Frandoloso will talk about the pathogenic mechanisms of H. parasuis and its interaction with the porcine immune system. He will also explore the current strategy to prevent Glässer’s disease through vaccination, including why the commercial classical vaccine has failed to provide full protection against the broad spectrum of virulent variations within this bacterium.  Dr. Frandoloso will present a very promising vaccine based on an engineered mutant TbpB antigen, which is able to induce full protection against experimental infections performed with two different variations of H. parasuis.

Dr. Frandoloso, DVM, PhD, is a scientist at the University of Passo Fundo, Brazil. His research activities have focussed on veterinary immunology and emerging bacterial respiratory diseases of swine. Dr. Frandoloso graduated in Veterinary Medicine in 2006 and completed his PhD in veterinary immunology at the University of León, Spain, in 2011. He is an international researcher associated with the Animal Health Department of the University of León and a corresponding academic of the Veterinary Science Academy of Castilla y León, Spain.

In 2017, Dr. Frandoloso did a sabbatical year at the University of Calgary and worked towards the development of a new vaccine designed to prevent Glässer’s disease.